"What's up?" I said to him.—"Just tired," he answered.

“出了什么事？”我对他说。— “只是累了，”他答道。

《柯林斯英汉双解大词典》

What's up with you, chuck?

你怎么了，亲爱的？

《牛津词典》

What's up with him? He looks furious.

他怎么了？他看上去怒气冲冲。

《牛津词典》

- BOY 2: How you guys doing?- Look who we just found. What's up, girl? Hey... Where you going?

VOA: standard.other

I wanted to show an example with real data that I computed and that's what's up on the screen.

我用真实的数据做了一个案例,请看上方的屏幕。

耶鲁公开课 - 金融市场课程节选

I can see something special is going on here. What's up with today?

我看到今天有些特别的活动。发生了什么？

关于世界地球日 - SpeakingMax英语口语达人

All the same, it would really be nice of Apple to let people know what's up.

ENGADGET: blogger-avatar

What's up: If you miss a period, pregnancy or menopause are two obvious explanations.

CNN: Your period: What's normal, what's not, what to do

Besides being the unofficial start of the weekend (party people, what's up?), it's time for another round of Ask Engadget.

ENGADGET: Ask Engadget: Best PMP for long flights?